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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPA1
All Species:
7.58
Human Site:
S158
Identified Species:
16.67
UniProt:
O60313
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60313
NP_056375.2
960
111631
S158
K
I
R
K
A
L
P
S
S
E
D
L
V
K
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087037
1092
125633
N235
K
I
R
K
A
L
P
N
S
E
D
L
V
K
L
Dog
Lupus familis
XP_534321
1175
133763
N318
K
I
R
K
A
L
P
N
S
E
D
L
A
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P58281
960
111321
S158
K
I
R
K
A
L
P
S
S
E
D
L
A
S
L
Rat
Rattus norvegicus
Q2TA68
960
111289
S158
K
I
R
K
A
L
P
S
S
E
D
L
A
N
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F499
977
113427
D157
K
L
I
K
A
L
P
D
A
D
D
L
A
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U3A7
966
111315
E157
K
L
A
S
A
L
P
E
L
E
E
I
A
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610941
933
107185
N150
E
V
G
S
L
V
K
N
A
I
E
V
A
K
D
Honey Bee
Apis mellifera
XP_396882
918
106720
Q150
I
K
A
A
E
V
N
Q
T
Q
A
G
L
D
I
Nematode Worm
Caenorhab. elegans
NP_495986
964
110236
Q164
F
K
Q
Q
K
E
D
Q
N
G
N
S
G
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32266
881
99159
Q156
D
D
D
E
S
K
R
Q
G
D
P
K
D
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.4
79.5
N.A.
96.3
95.9
N.A.
N.A.
85.6
N.A.
79
N.A.
52.1
55
50.9
N.A.
Protein Similarity:
100
N.A.
87.6
80.5
N.A.
97.9
97.8
N.A.
N.A.
92.3
N.A.
88.8
N.A.
69
73.9
69.2
N.A.
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
86.6
80
N.A.
N.A.
60
N.A.
46.6
N.A.
6.6
0
0
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
86.6
80
N.A.
N.A.
80
N.A.
66.6
N.A.
53.3
33.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
10
64
0
0
0
19
0
10
0
55
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
0
0
0
10
10
0
19
55
0
10
19
19
% D
% Glu:
10
0
0
10
10
10
0
10
0
55
19
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
10
0
0
0
0
0
10
10
0
10
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
46
10
0
0
0
0
0
0
10
0
10
0
0
10
% I
% Lys:
64
19
0
55
10
10
10
0
0
0
0
10
0
55
0
% K
% Leu:
0
19
0
0
10
64
0
0
10
0
0
55
10
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
28
10
0
10
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
64
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
10
10
0
0
0
28
0
10
0
0
0
0
0
% Q
% Arg:
0
0
46
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
19
10
0
0
28
46
0
0
10
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
19
0
0
0
0
0
10
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _